Publications
Analysis of Breast Cancer Mortality in the US-1975 to 2019.Caswell-Jin JL, Sun LP, Munoz D, Lu Y, Li Y, Huang H, Hampton JM, Song J, Jayasekera J, Schechter C, Alagoz O, Stout NK, Trentham-Dietz A, Lee SJ, Huang X, Mandelblatt JS, Berry DA, Kurian AW, Plevritis SK.JAMA. 2024 Jan 16;331(3):233-241. doi: 10.1001/jama.2023.25881.PMID: 38227031
Phenotyping EMT and MET cellular states in lung cancer patient liquid biopsies at a personalized level using mass cytometry.Karacosta LG, Pancirer D, Preiss JS, Benson JA, Trope W, Shrager JB, Sung AW, Neal JW, Bendall SC, Wakelee H, Plevritis SK.Sci Rep. 2023 Dec 8;13(1):21781. doi: 10.1038/s41598-023-46458-5.PMID: 38065965
Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer.Brennan K, Espín-Pérez A, Chang S, Bedi N, Saumyaa S, Shin JH, Plevritis SK, Gevaert O, Sunwoo JB, Gentles AJ.Genome Med. 2023 Nov 17;15(1):98. doi: 10.1186/s13073-023-01236-w.PMID: 37978395
The colocatome as a spatial -omic reveals shared microenvironment features between tumour-stroma assembloids and human lung cancer.Bouchard G, Zhang W, Li I, Ilerten I, Bhattacharya A, Li Y, Trope W, Shrager JB, Kuo C, Tian L, Giaccia AJ, Plevritis SK.bioRxiv. 2023 Sep 12:2023.09.11.557278. doi: 10.1101/2023.09.11.557278. Preprint.PMID: 37745466
p53 governs an AT1 differentiation programme in lung cancer suppression.Kaiser AM, Gatto A, Hanson KJ, Zhao RL, Raj N, Ozawa MG, Seoane JA, Bieging-Rolett KT, Wang M, Li I, Trope WL, Liou DZ, Shrager JB, Plevritis SK, Newman AM, Van Rechem C, Attardi LD.Nature. 2023 Jul;619(7971):851-859. doi: 10.1038/s41586-023-06253-8. Epub 2023 Jul 19.PMID: 37468633
Organization of the human intestine at single-cell resolution.Hickey JW, Becker WR, Nevins SA, Horning A, Perez AE, Zhu C, Zhu B, Wei B, Chiu R, Chen DC, Cotter DL, Esplin ED, Weimer AK, Caraccio C, Venkataraaman V, Schürch CM, Black S, Brbić M, Cao K, Chen S, Zhang W, Monte E, Zhang NR, Ma Z, Leskovec J, Zhang Z, Lin S, Longacre T, Plevritis SK, Lin Y, Nolan GP, Greenleaf WJ, Snyder M.Nature. 2023 Jul;619(7970):572-584. doi: 10.1038/s41586-023-05915-x. Epub 2023 Jul 19.PMID: 37468586
Risk Model-Based Lung Cancer Screening : A Cost-Effectiveness Analysis.Toumazis I, Cao P, de Nijs K, Bastani M, Munshi V, Hemmati M, Ten Haaf K, Jeon J, Tammemägi M, Gazelle GS, Feuer EJ, Kong CY, Meza R, de Koning HJ, Plevritis SK, Han SS.Ann Intern Med. 2023 Mar;176(3):320-332. doi: 10.7326/M22-2216. Epub 2023 Feb 7.PMID: 36745885
Post-infusion CAR TReg cells identify patients resistant to CD19-CAR therapy.Good Z, Spiegel JY, Sahaf B, Malipatlolla MB, Ehlinger ZJ, Kurra S, Desai MH, Reynolds WD, Wong Lin A, Vandris P, Wu F, Prabhu S, Hamilton MP, Tamaresis JS, Hanson PJ, Patel S, Feldman SA, Frank MJ, Baird JH, Muffly L, Claire GK, Craig J, Kong KA, Wagh D, Coller J, Bendall SC, Tibshirani RJ, Plevritis SK, Miklos DB, Mackall CL.Nat Med. 2022 Sep;28(9):1860-1871. doi: 10.1038/s41591-022-01960-7. Epub 2022 Sep 12.PMID: 36097223
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.Zhang W, Li I, Reticker-Flynn NE, Good Z, Chang S, Samusik N, Saumyaa S, Li Y, Zhou X, Liang R, Kong CS, Le QT, Gentles AJ, Sunwoo JB, Nolan GP, Engleman EG, Plevritis SK.Nat Methods. 2022 Jun;19(6):759-769. doi: 10.1038/s41592-022-01498-z. Epub 2022 Jun 2.PMID: 35654951
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.Reticker-Flynn NE, Zhang W, Belk JA, Basto PA, Escalante NK, Pilarowski GOW, Bejnood A, Martins MM, Kenkel JA, Linde IL, Bagchi S, Yuan R, Chang S, Spitzer MH, Carmi Y, Cheng J, Tolentino LL, Choi O, Wu N, Kong CS, Gentles AJ, Sunwoo JB, Satpathy AT, Plevritis SK, Engleman EG.Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6.PMID: 35525247
Reconstructing codependent cellular cross-talk in lung adenocarcinoma using REMI.Yu A, Li Y, Li I, Ozawa MG, Yeh C, Chiou AE, Trope WL, Taylor J, Shrager J, Plevritis SK.Sci Adv. 2022 Mar 18;8(11):eabi4757. doi: 10.1126/sciadv.abi4757. Epub 2022 Mar 18.PMID: 35302849
Visualization, benchmarking and characterization of nested single-cell heterogeneity as dynamic forest mixtures.Anchang B, Mendez-Giraldez R, Xu X, Archer TK, Chen Q, Hu G, Plevritis SK, Motsinger-Reif AA, Li JL.Brief Bioinform. 2022 Mar 10;23(2):bbac017. doi: 10.1093/bib/bbac017.PMID: 35192692
Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge.Bouchard G, Garcia-Marques FJ, Karacosta LG, Zhang W, Bermudez A, Riley NM, Varma S, Mehl LC, Benson JA, Shrager JB, Bertozzi CR, Pitteri SJ, Giaccia AJ, Plevritis SK.Cancer Res. 2022 Feb 15;82(4):648-664. doi: 10.1158/0008-5472.CAN-21-1705.PMID: 34853070
A Cost-Effectiveness Analysis of Lung Cancer Screening With Low-Dose Computed Tomography and a Diagnostic Biomarker.Toumazis I, Erdogan SA, Bastani M, Leung A, Plevritis SK.JNCI Cancer Spectr. 2021 Oct 6;5(6):pkab081. doi: 10.1093/jncics/pkab081. eCollection 2021 Dec.PMID: 34738073
Cost-effectiveness Evaluation of the 2021 US Preventive Services Task Force Recommendation for Lung Cancer Screening.Toumazis I, de Nijs K, Cao P, Bastani M, Munshi V, Ten Haaf K, Jeon J, Gazelle GS, Feuer EJ, de Koning HJ, Meza R, Kong CY, Han SS, Plevritis SK.JAMA Oncol. 2021 Dec 1;7(12):1833-1842. doi: 10.1001/jamaoncol.2021.4942.PMID: 34673885
Evaluation of Alternative Diagnostic Follow-up Intervals for Lung Reporting and Data System Criteria on the Effectiveness of Lung Cancer Screening.Bastani M, Toumazis I, Hedou' J, Leung A, Plevritis SK.J Am Coll Radiol. 2021 Dec;18(12):1614-1623. doi: 10.1016/j.jacr.2021.08.001. Epub 2021 Aug 19.PMID: 34419477
A risk-based framework for assessing real-time lung cancer screening eligibility that incorporates life expectancy and past screening findings.Toumazis I, Alagoz O, Leung A, Plevritis SK.Cancer. 2021 Dec 1;127(23):4432-4446. doi: 10.1002/cncr.33835. Epub 2021 Aug 12.PMID: 34383299
Reflecting on 20 years of breast cancer modeling in CISNET: Recommendations for future cancer systems modeling efforts.Trentham-Dietz A, Alagoz O, Chapman C, Huang X, Jayasekera J, van Ravesteyn NT, Lee SJ, Schechter CB, Yeh JM, Plevritis SK, Mandelblatt JS; Breast Working Group of the Cancer Intervention and Surveillance Modeling Network (CISNET).PLoS Comput Biol. 2021 Jun 17;17(6):e1009020. doi: 10.1371/journal.pcbi.1009020. eCollection 2021 Jun.PMID: 34138842